"Human Nature" is a song recorded by American singer Madonna for her sixth studio album Bedtime Stories (1994). It was written as an answer song to her critics, who had panned her provocative image of the previous two years and Madonna's release of sexually explicit works. Written and produced by Madonna and Dave Hall, "Human Nature" includes a looping sample from Main Source's 1994 track "What You Need", therefore its writers Shawn McKenzie, Kevin McKenzie and Michael Deering are also credited. The track was released on June 6, 1995, by Maverick Records as the fourth and final single from Bedtime Stories.

"Human Nature" is an R&B track where the sound of drums and the sample is heard looping throughout, with Madonna sarcastically asking rhetorical questions based on her real-life actions over the prior two years. The song received mostly positive reviews from music critics who have later noted its anthemic and empowering nature. "Human Nature" became a moderate hit in the United States, peaking at number 46 on the Billboard Hot 100 and at number two on the Hot Dance Club Play chart. In the United Kingdom, the single entered the chart and peaked at number eight and it also charted within the Top 10 in Italy and the Top 20 in Australia.

The accompanying music video was directed by Jean-Baptiste Mondino, and features Madonna and her dancers dressed in latex and leather, while executing highly choreographed dance routines. Inspired by S&M imagery, the video later influenced the work of singers Rihanna and Christina Aguilera. Madonna has performed "Human Nature" on four of her concert tours, most recently on the 2019–20 Madame X Tour. In 2012, during The MDNA Tour, the performance of the song became the subject of controversy, when the singer exposed her nipples during a show in Istanbul.